Laboratory Excellence and AccreditationIntroduction to Method Validation
Validation demonstrates that a method does what the laboratory says it does, for the samples it will actually see. This course covers the practice. Delegates work through the validation parameters and what each one answers, including selectivity, linearity and range, accuracy and trueness, precision under repeatability and intermediate conditions, limits of detection and quantitation, and robustness. The distinction between validation and verification of a standard method is made clear, since laboratories routinely do more work than needed for the latter and less than needed for the former. The course closes on the validation plan and report, and on the decision of when a change to a method requires revalidation.
Course objectives
- Distinguish validation from verification of a standard method
- Select the validation parameters relevant to a given method
- Assess selectivity, linearity and working range
- Determine accuracy, trueness and precision
- Establish limits of detection and quantitation defensibly
- Test robustness against realistic variation
- Write a validation plan and report, and decide when to revalidate
Who should attend
- Analysts and method development staff
- Laboratory quality and technical managers
- Technical signatories
- Internal auditors of laboratories
- Graduate scientists entering laboratory roles
Course outline
- 01What validation demonstrates, and to whom
- 02Validation against verification of a standard method
- 03Selectivity, linearity and working range
- 04Accuracy, trueness and bias
- 05Precision: repeatability and intermediate conditions
- 06Limits of detection and quantitation
- 07Robustness testing
- 08The validation plan, the report, and when to revalidate
Scheduled sessions
| Dates | Venue | Format | Price | Register |
|---|---|---|---|---|
| 28 to 29 September 2026 | Windhoek, Namibia | Classroom | R11,950 per delegate | Register Now |
| 3 to 4 November 2026 | Online | Online | R6,500 per delegate | Register Now |
| 3 to 4 March 2027 | Cape Town, South Africa | Classroom | R11,950 per delegate | Register Now |